Ashim Mitra, Chi H. Lee, Kun Cheng's Advanced Drug Delivery PDF

By Ashim Mitra, Chi H. Lee, Kun Cheng

ISBN-10: 1118022661

ISBN-13: 9781118022665

Provides either basics and new and rising applications

Advanced Drug Delivery brings readers absolutely modern with the kingdom of the technological know-how, providing the fundamentals, formula suggestions, and healing functions of complicated drug supply. The publication demonstrates how middle techniques of pharmaceutical sciences, chemistry, and molecular biology might be mixed and utilized so that it will spark novel rules to layout and advance complex drug supply structures for the therapy of a extensive variety of human diseases.

Advanced Drug Delivery beneficial properties contributions from a world group of pharmaceutical scientists. Chapters mirror a radical evaluation and research of the literature in addition to the authors' firsthand adventure constructing drug supply platforms. The e-book is split into 4 parts:

  • Part I, creation and fundamentals of complex Drug Delivery, explores physiological obstacles, balance, transporters, and biomaterials in drug delivery
  • Part II, thoughts for complex Drug Delivery, deals demonstrated and confirmed concepts for complicated supply of either small molecules and macromolecules
  • Part III, Translational examine of complicated Drug Delivery, specializes in regulatory concerns and translational functions of complex drug supply structures for the remedy of cardiovascular ailments, melanoma, sexually transmitted illnesses, ophthalmic illnesses, and mind diseases
  • Part IV, destiny purposes of complex Drug supply in rising study Areas, examines stem mobilephone study, cell-based therapeutics, tissue engineering, and molecular imaging

Each bankruptcy offers goals and evaluation inquiries to aid readers clutch key innovations and check their wisdom as they development throughout the book.

Advanced Drug Delivery is suggested for graduates and upper-level undergraduates within the pharmaceutical sciences who want a stable starting place within the fundamentals. it's also steered for pharmaceutical execs who are looking to benefit from new and rising purposes in complex drug supply systems.

Show description

Read or Download Advanced Drug Delivery PDF

Similar pharmacy books

Integrated strategies for drug discovery using mass - download pdf or read online

New suggestions and methods for brand new fast paced discovery strategy this present day, the strain is on for high-throughput ways to speed up the iteration, identity, and optimization of molecules with fascinating drug houses. As conventional tools of study develop into antiquated, new analytical thoughts and strategies are essential to meet pattern throughput specifications and manpower constraints.

Pharmaceutical product strategy : using dynamic modeling for - download pdf or read online

"A uncomplicated company modeling publication can provide you technical info on employing enterprise types, and a easy advertising and marketing booklet can provide you an realizing of branding, yet none of them disguise the problems singular to the pharmaceutical undefined. targeting those distinctive concerns, Pharmaceutical Product technique: utilizing Dynamic Modeling for powerful model making plans offers precise strategies to the demanding situations concerned with product launches, the emblem making plans technique, and the modeling of sufferer, doctor, and prescription info to foretell a product's good fortune.

Download PDF by None: BMA Concise Guide to Medicine & Drugs

Discover what you are taking with the BMA Concise advisor to drugs and medicine, the short reference consultant to greater than 2,500 prescription and over the counter medicinal drugs from Britain's best clinical authority, the BMA. Jargon-free and easy-to-follow, get the entire very important info you wish on modern medicines quickly.

Handbook of Polyester Drug Delivery Systems - download pdf or read online

Within the quest for cutting edge drug supply platforms trying to meet the unmet wishes in pharmaceutical area, learn has taken a way more complex direction that poses an important problem for translation. regardless of the development made with novel fabrics, polyesters nonetheless stay on the helm of drug supply applied sciences.

Additional info for Advanced Drug Delivery

Example text

Journal of Pharmacology and Experimental Therapeutics, 123, 81–88. 67. , et al. (1959). On the mechanism of intestinal absorption of drugs. Journal of Pharmacology and Experimental Therapeutics, 125, 275–282. 68. , et al. (1971). Drug absorption IV. Influence of pH on absorption kinetics of weakly acidic drugs. Journal of Pharmacy & Pharmaceutical Sciences, 60, 1160–1163. 69. H. (1995). Species similarities and differences in pharmacokinetics. Drug Metabolism and Disposition, 23, 1008–1021. 70.

1965). Permeability characteristics of the human small intestine. Journal of Clinical Investigation, 44, 1935–1944. 11. F. (1977). Measurements of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). II. Application to normal and abnormal permeability states in man and animals. Gastroenterology, 73, 247–251. 12. , X. (2009). Estimation of the theoretical pore sizes of the porcine oral mucosa for permeation of hydrophilic permeants. Archives of Oral Biology, 54, 577–582.

Some common approaches frequently implemented for enhancing drug solubility are outlined below. 1 Prodrugs Prodrugs are compounds that are not biologically active by themselves but should be transformed into active products by chemical or enzymatic reactions [24–26]. Prodrugs can be classified into four major categories [27]: 1) carrier linked (active agent is linked to a carrier whose activation occurs by hydrolysis, oxidation, or reduction), 2) bioprecursors (which do not contain a premoiety yet are activated by hydration, oxidation, or reduction), 3) drug-polymer conjugates (where the carrier is a macromolecule such as a polyethylene glycol), and 4) drugantibody conjugates (where the carrier is an antibody raised against tumor cells).

Download PDF sample

Advanced Drug Delivery by Ashim Mitra, Chi H. Lee, Kun Cheng


by Mark
4.2

Rated 4.82 of 5 – based on 8 votes