Ashim Mitra, Chi H. Lee, Kun Cheng's Advanced Drug Delivery PDF
By Ashim Mitra, Chi H. Lee, Kun Cheng
Provides either basics and new and rising applications
Advanced Drug Delivery brings readers absolutely modern with the kingdom of the technological know-how, providing the fundamentals, formula suggestions, and healing functions of complicated drug supply. The publication demonstrates how middle techniques of pharmaceutical sciences, chemistry, and molecular biology might be mixed and utilized so that it will spark novel rules to layout and advance complex drug supply structures for the therapy of a extensive variety of human diseases.
Advanced Drug Delivery beneficial properties contributions from a world group of pharmaceutical scientists. Chapters mirror a radical evaluation and research of the literature in addition to the authors' firsthand adventure constructing drug supply platforms. The e-book is split into 4 parts:
- Part I, creation and fundamentals of complex Drug Delivery, explores physiological obstacles, balance, transporters, and biomaterials in drug delivery
- Part II, thoughts for complex Drug Delivery, deals demonstrated and confirmed concepts for complicated supply of either small molecules and macromolecules
- Part III, Translational examine of complicated Drug Delivery, specializes in regulatory concerns and translational functions of complex drug supply structures for the remedy of cardiovascular ailments, melanoma, sexually transmitted illnesses, ophthalmic illnesses, and mind diseases
- Part IV, destiny purposes of complex Drug supply in rising study Areas, examines stem mobilephone study, cell-based therapeutics, tissue engineering, and molecular imaging
Each bankruptcy offers goals and evaluation inquiries to aid readers clutch key innovations and check their wisdom as they development throughout the book.
Advanced Drug Delivery is suggested for graduates and upper-level undergraduates within the pharmaceutical sciences who want a stable starting place within the fundamentals. it's also steered for pharmaceutical execs who are looking to benefit from new and rising purposes in complex drug supply systems.
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Additional info for Advanced Drug Delivery
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Some common approaches frequently implemented for enhancing drug solubility are outlined below. 1 Prodrugs Prodrugs are compounds that are not biologically active by themselves but should be transformed into active products by chemical or enzymatic reactions [24–26]. Prodrugs can be classified into four major categories : 1) carrier linked (active agent is linked to a carrier whose activation occurs by hydrolysis, oxidation, or reduction), 2) bioprecursors (which do not contain a premoiety yet are activated by hydration, oxidation, or reduction), 3) drug-polymer conjugates (where the carrier is a macromolecule such as a polyethylene glycol), and 4) drugantibody conjugates (where the carrier is an antibody raised against tumor cells).
Advanced Drug Delivery by Ashim Mitra, Chi H. Lee, Kun Cheng